In Focus: Cryogenic containment for cell and gene therapies

The complex manufacturing processes of cell and gene therapies often require extremely low temperatures. This requires cryogenic containers, which allow for the storage and ...

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In Focus: Scalability

Cell expansion allows researchers and cell therapy developers to generate the necessary quantity of cells for their applications. However, cell expansion comes with several challenges, ...

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In Focus: Expansion and downstream processing of hiPSCs

Human induced pluripotent stem cells (hiPSCs) hold immense promise for widespread cell therapies, but scaling their production for clinical use is a major obstacle. A novel solution ...

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In Focus: Automating cell expansion

In this In Focus feature, we’re investigating cell culture expansion processes and how to automate them in a system that replicates the physiological environment.  Cell culture and ...

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In Focus: GMP-grade cell culture

Good manufacturing practice (GMP) encompasses a set of quality control and assurance standards that ensure products used in various biopharmaceutical and biotechnological applications ...

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In Focus: Small molecules

Small molecules can be used throughout the development of induced pluripotent stem-cell derived cell therapies for reprogramming, maintenance and differentiation. But it can often be ...

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In Focus: AI for cell culture imaging and analysis

Live cell imaging and analysis is a major component of cell therapy development, allowing measurement of critical factors such as cell proliferation, cellular kinetics, protein ...

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In Focus: Raw materials

As cell therapies progress from the lab to the clinic, the raw material requirements change. In the clinical and commercial stages they need to meet higher safety and quality conditions ...

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In Focus: Growing organoids

Organoids are three-dimensional, miniaturized tissue constructs that can be generated from pluripotent stem cells, adult stem cells, or primary tissues and closely mimic the ...

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In Focus: CAR-T cell therapy

Despite the great clinical success of CAR-T therapies, due to their complexity manufacturers continue to face a number of challenges, including contamination, variability and cost. In ...

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In Focus: iPSCs for cell therapy

With their unlimited proliferation capacity and ability to differentiate into nearly any cell type in the body, induced pluripotent stem cells (iPSCs) have the potential to provide an ...

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In Focus: cell culture quality control

Cell culture quality control is a critical step for the development, manufacture and commercialization of any cell-based therapy. However, it is a time-consuming and labor-intensive ...

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In Focus: automated process

In the manufacturing of cell therapies, fill and finish is a critical, high-value step for ensuring final products are safe, efficacious and standardized. Fill and finish is a highly ...

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In Focus: Reagent consistency

How can cell therapy manufacturers guarantee consistent, high-quality results for their final products? In this In Focus feature, we are diving deep into the topic of reagent ...

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In Focus: scaling up and out

The cell and gene therapy industry has undergone remarkable advances in the last decade, bringing life-saving treatments to patients with diseases that were originally thought to be ...

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In Focus: sustainability in cell and gene therapy

The advanced therapies and pharmaceuticals industry are under constant pressure to innovate. With the common goal of bringing life-saving treatments to patients, the industry often ...

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In Focus: electroporation

Transfection is the process of introducing foreign material – generally nucleic acids (DNA or RNA) – into cells. This allows for the study of gene function and protein ...

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In Focus: AAV gene therapy

Adeno-associated viruses (AAVs) are rapidly becoming a promising means of delivering gene therapies to defective tissues in the human body. To this end, scalable and cost-effective AAV ...

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In Focus: decentralized manufacturing

Decentralized manufacturing, also referred to as ‘redistributed manufacturing’, divides the manufacturing capacity for cell and gene therapies between multiple sites. This strategy can ...

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In Focus: cell cryopreservation and cold chain

When thinking about the commercial and clinical development of cell therapies, cryopreservation and cold chain processes are essential elements to consider. Optimizing the cold chain ...

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In Focus: cellular starting materials for cell therapies

Cellular starting materials are a crucial aspect in the development of cell therapies. However, starting materials that involve a cell preparation can be a significant source of ...

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In focus: packaging and producer cell lines

Lentiviral vectors are often a popular choice for transient transfection when it comes to developing cell therapies. However, this method can often be expensive, difficult to reproduce ...

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In focus: cryopreservation

From raw materials to the finished product, cryopreservation touches every stage of the cell therapy production process. What should you consider when validating your cryopreservation ...

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In focus: applications in cardiology

The use of 3D printing in cardiology has grown over recent years, from scientists working to fabricate cardiac tissues with bioprinting techniques to surgical teams 3D printing complex ...

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In focus: the additive response to COVID-19

In the face of the COVID-19 pandemic, innovators are finding novel ways to apply 3D-printed solutions to assist the international response to coronavirus. From meeting PPE demands to ...

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In focus: nanomedicine in organ transplantation and regenerative surgery

This month, we’ve partnered with the journal Nanomedicine to bring you a special editorial in focus looking at the role nanomedicine can play in organ transplantation and ...

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In focus: raw materials

This month, we are focusing on the challenges in selecting and securing your raw materials; access an exclusive infographic, journal content and more! The consistent manufacture of cell ...

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In focus: the regenerative medicine landscape in Asia

This month, we are focusing on regenerative medicine developments, progress and regulations across Asia; access exclusive infographics, journal content and more! The regenerative ...

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In focus: applications in neuro R&D

Hear from the experts as 3DMedNet discusses the use of 3D printing in neuro-based disciplines, from the bioprinting of neural tissues to the use of 3D printing in affordable ...

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In focus: embryonic stem cells

This month, we are focusing on embryonic stem cells; access exclusive interviews, infographics, journal content and more. Embryonic stem cells (ESCs) were first cultured in 1981 and ...

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In focus: applications in pediatrics

Find out more about 3D printing in pediatrics as 3DMedNet invites the experts, from pharmaceutical design to surgery, to discuss how 3D printing is being used to solve complex pediatric ...

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In focus: disrupting dentistry

Discover expert and industry insights on the effect 3D printing is having on dentistry, disrupting dental practice and improving oral health. 3D printing technologies have had a ...

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In focus: applications in oncology

In this feature, 3DMedNet consults oncology experts about how 3D printing is being used to revolutionize cancer detection, treatment and research. According to statistics on the World ...

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In focus: regenerative pharmacology

This month, we are focusing on regenerative pharmacology; access exclusive interviews, infographics, journal content and more, in partnership with RxNet, the network for pharma R&D. ...

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In focus: regenerative materials

This month, we are focusing on regenerative materials; access exclusive interviews, videos, journal content and more. Regenerative materials offer a controlled and directed method of ...

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Award for Cultivating Excellence 2018: BellaSeno GmbH

In this feature, learn more about our fantastic 2018 winners, BellaSeno GmbH, and learn more about the rest of our finalists. In this feature, learn more about our fantastic 2018 ...

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In focus: cell therapy development

This month, we are focusing on cell therapy development; access exclusive interviews, infographics, journal content and more. Successful cell therapy development involves a number of ...

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Low Vision Awareness Month 2018

With this exclusive content, find out more about what lessons can be learned from the Japanese first-in-human age-related macular degeneration trial. For Low Vision Awareness Month ...

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In focus: rare diseases

Check out this round-up of top content for Rare Disease Day 2018! In honor of Rare Disease Day 2018, we’ve collated some of our top content highlighting how regenerative medicine ...

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