Transcriptional and epigenetic mechanisms of cellular reprogramming to induced pluripotency
This Epigenomics Review presents the understanding to date on the transcriptional and epigenetic regulators initiating pluripotency, and discusses how variability in epigenetic states impacts iPSCs’ inherent biological properties. By Mark van den Hurk, Gunter Kenis, Cedric Bardy et al. from Maastricht University (The Netherlands) and the Salk Institute for Biological Studies (La Jolla, CA, USA).
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