Controlled mechanotransduction in therapeutic MSCs: can remotely controlled magnetic nanoparticles regenerate bones?

Free-to-access editorial on use of controlled magnetic nanoparticles for bone regeneration, written by James Henstock and Alicia El Haj

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Jun 17, 2015
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To inform cells of their physical environment, complex loading forces are transduced through tissue affecting homeostasis, regulation of cell behavior, differentiation and extracellular matrix composition.

Mechanotransduction is now developing into a recognized route for delivering tissue-forming stimuli to therapeutic cells. In an editorial in the latest issue of Regenerative Medicine (Volume 10 Issue 4), entitled ‘Controlled mechanotransduction in therapeutic MSCs: can remotely controlled magnetic nanoparticles regenerate bones?’, Alicia El Haj and James Henstock from Keele University Medical School, UK, discuss how these biomechanical pathways can be exploited to resolve long-standing challenges in regenerative medicine: the optimal construction, repair and integration of tissues in the body.

Read the full, free-to-access editorial here.

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Regenerative Medicine

Journal, Future Science Group

Regenerative Medicine is an award-winning peer-reviewed journal, in print and web formats. The journal provides a forum to address the important challenges and advances in stem cell research and regenerative medicine, delivering this essential information in concise, clear and attractive article formats. Among other indexing services Regenerative Medicine is listed by MEDLINE/Index Medicus, EMBASE/Excerpta Medica, Chemical Abstracts, Science Citation Index Expanded™ (SciSearch®), Emcare, Biological Abstracts, BIOSIS Previews, Biotechnology Citation Index®, Journal Citation Reports/Science Edition®, Scopus® with an Impact Factor of 2.786 (2014). Each issue contains expertly drafted Reviews, Original Research articles, Perspectives, Editorials, topical insight from international leaders in their field, and additional added-value content. The Senior Editor of the journal is Professor Chris Mason, University College London. You can find out more about Regenerative Medicine at our website (, where you can find the aims and scope of the journal and details of our international editorial board.

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