Rebuilding the infarcted heart with noncellular material

In this free-to-access Editorial, Robert A Kloner et al. from University of Southern California, HMRI Cardiovascular Research Institute and University of Southern California (all CA, USA) discuss the need to pursue non-cellular therapeutic methods for heart repair. Hundreds of studies have attempted to regenerate cardiac tissue following injury by injecting various types of cells, such as MSCs, ESC-derived cells, immature progenitor cells and fetal stem cells, into the vasculature or directly into the wall of infarcted hearts. In this free-to-access Editorial, Robert A Kloner, Wangde Dai, Jianru Shi, Sharon Hale and Marie Csete from University of Southern California, HMRI Cardiovascular...