Oxygen-controlled automated neural differentiation of mouse embryonic stem cells
In this research article, published in Regenerative Medicine, learn more about an automation platform capable of maintaining oxygen tension control during both the cell-culture and liquid-handling. This article has been made free exclusively for members of RegMedNet.
Embryonic stem cells are showing promise as a therapeutic avenue for a number of conditions, but widespread application of the technology will rely on robust, reproducible and high-yield product methods. Automation and oxygen tension control are two tools that provide significant improvements to the reproducibility and efficiency of stem cell production processes.
In this research article, from an international team at The Advanced Centre for Biochemical Engineering, University College London (London, UK), and Biomedical Research Division, Centro Medico Nacional ‘20 de Noviembre’ – ISSSTE (Mexico City, Mexico), learn more about the development of an automated platform for maintaining oxygen tension control for 2D embryonic cell culture and differentiation. Use of the platform at the cell culture and liquid handling stages results in improvements in the differentiation efficiency.