Physical and mechanical factors involved in tissue engineering of cartilage
Free to access Review by Carrie Gaut and Kiminobu Sugaya focuses on the effect that the different structural properties of scaffold can have on regulation of mesenchymal stem cell fate, and how this is currently being applied to cartilage tissue engineering research.
To date, tissue engineering approaches to treat osteoarthritis, an articular cartilage defects that has a significant and negative impact on the economy and quality of life worldwide, have mainly focused on stem cell proliferation and differentiation, and scaffolding. This Review by Carrie Gaut (Ciudad de Saber, Rep. de Panama) and Kiminobu Sugaya (University of Central Florida College of Medicine, FL, USA) discusses the properties to consider when tissue engineering cartilage.
Gaut C, Sugaya K. Critical review on the physical and mechanical factors involved in tissue engineering of cartilage. Regen. Med. 10(5), 665–679 (2015). Author for correspondence: firstname.lastname@example.org.