Comparing immunogenic and immunomodulatory properties of iPSCs versus bone marrow-derived MSCs

Have you read this article? ‘Induced pluripotent stem cells have similar immunogenic and more potent immunomodulatory properties compared with bone marrow-derived stromal cells in vitro’, published by Regenerative Medicine earlier this year, found that iPSCs had similar immunogenic properties but more potent immunomodulatory effects than MSCs. Find the abstract and link to the free-to-access article below: Aim: To evaluate the in vitro immunogenic and immunomodulatory properties of induced pluripotent stem cells (iPSCs) compared with bone marrow-derived mesenchymal stromal cells (MSCs). Materials & Methods: Mouse embryonic fibroblasts (MEFs) were isolated from C3HeB/FeJ and C57BL/6J mice, and reprogrammed to generate iPSCs. Mixed...