Reconstructing 3D neural tissue with biocompatible nanofiber scaffolds and hydrogels

Research work recently published in the Journal of Neural Engineering demonstrates a strategy for reconstructing three-dimensional (3D) neural tissue architecture using patterned nanofiber scaffolding within 3D hydrogel structures. This composite architecture can guide and enhance neurite outgrowth, particularly when functionalized with certain types of cell signaling and adhesion molecules. This may have applications for in vitro neural models as well as for in vivo regeneration and restoration of neural pathways in damaged or diseased neural tissue.

Jan 10, 2015

Richard McMurtrey

Director, Institute of Neural Regeneration & Tissue Engineering

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