Examining the effects of preoperative medication in regenerative dental medicine

New study investigates the osteoinductive effects of dexamethasone during primary cell culture of human dental pulp stem cells A new study from Silvio Duailibi and colleagues at UNIFESP (Brazil) has assessed the osteoinductive effect of dexamethasone (DEX) administered as a preoperative medication in primary cell culture of human dental pulp stem cells (hDPSCs).During tooth extraction for third molar cell culture, preoperative medication might be used to reduce trauma and pain. DEX is a long-acting steroid used as an anti-inflammatory administered around 1 hour prior to surgery. Furthermore, DEX is known to induce osteoblast differentiation of mesenchymal stem cells and osteogenic...