The likely role of proteolytic enzymes in unwanted differentiation of stem cells in culture

Vanessa Penna et al. from the Federal University of Sao Paulo and CTCmol look at the use of proteolytic enzymes in cell culture and tissue engineering

Jun 05, 2015

In this free-to-read review in Future Science OA, Penna et al. examine the possible mechanisms of cellular change that might occur owing to the use of proteolytic enzymes in cell culture. They conclude that the use of proteolytic enzymes needs to be reassessed to ensure clinical safety, and highlight cell sheets and hydrogel 3D culture as possible alternatives. You can read the full review here: Any comments welcome!

Future Science OA

Open Access Journal, Future Science Group

Future Science OA is an online, open access (CC-BY), peer-reviewed title from Future Science Group. The journal’s broad coverage includes all areas of biotechnology and medicine, as well as topics in biological, life and physical sciences that are of relevance to human health. The journal embraces the importance of publishing all good-quality research with the potential to further the progress of medical science. All original research articles that have been conducted with scientific rigor and research integrity will be considered. The journal also features review articles, editorials and perspectives, providing readers with a leading source of commentary and analysis.

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