Conducting polymer-based multilayer films for instructive biomaterial coatings
New research piece published in Future Science OA reports on a new method of aligning cells on biomaterials.
Research performed by John G Hardy and colleagues at The University of Texas at Austin (TX, USA) has demonstrated a new method of creating instructive biomaterial coatings for cell alignment, an important feature for a variety of tissues. Designing conducting composite biomaterials based on multilayer films of poly(3.4-ethylenedioxythiophene) derivatives, chitosan and gelatin layer by layer, they demonstrated that fibroblasts both adhered to, and aligned and proliferated on, the films. This was enhanced using a DC current.
The process uses dip coating, an attractive method owing to its ease and scalability. The group expects to be able to tailor the properties of the films to specific niche applications and, potentially, specific patients.
Read the full piece here.
John G Hardy, Hetian Li, Jacqueline K Chow, Sydney A Geissler, Austin B McElroy, Lindsey Nguy, Derek S Hernandez, Christine E Schmidt. Conducting polymer-based multilayer films for instructive biomaterial coatings. Future Science OA FSO79, doi:10.4155/fso.15.79 (2015) (Epub ahead of print).