Conducting polymer-based multilayer films for instructive biomaterial coatings

New research piece published in Future Science OA reports on a new method of aligning cells on biomaterials.

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Nov 03, 2015

Research performed by John G Hardy and colleagues at The University of Texas at Austin (TX, USA) has demonstrated a new method of creating instructive biomaterial coatings for cell alignment, an important feature for a variety of tissues. Designing conducting composite biomaterials based on multilayer films of poly(3.4-ethylenedioxythiophene) derivatives, chitosan and gelatin layer by layer, they demonstrated that fibroblasts both adhered to, and aligned and proliferated on, the films. This was enhanced using a DC current.

The process uses dip coating, an attractive method owing to its ease and scalability. The group expects to be able to tailor the properties of the films to specific niche applications and, potentially, specific patients.

Read the full piece here.

John G Hardy, Hetian Li, Jacqueline K Chow, Sydney A Geissler, Austin B McElroy, Lindsey Nguy, Derek S Hernandez, Christine E Schmidt. Conducting polymer-based multilayer films for instructive biomaterial coatings. Future Science OA FSO79, doi:10.4155/fso.15.79 (2015) (Epub ahead of print).

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Future Science OA

Open Access Journal, Future Science Group

Future Science OA is an online, open access (CC-BY), peer-reviewed title from Future Science Group. The journal’s broad coverage includes all areas of biotechnology and medicine, as well as topics in biological, life and physical sciences that are of relevance to human health. The journal embraces the importance of publishing all good-quality research with the potential to further the progress of medical science. All original research articles that have been conducted with scientific rigor and research integrity will be considered. The journal also features review articles, editorials and perspectives, providing readers with a leading source of commentary and analysis.

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