On the hunt for the perfect natural tooth scaffold
New research suggests we are far from having a perfect method to decellularize tooth tissue
A new research article published in Future Science OA has attempted to answer the challenge of discovering the best process for creating a natural scaffold for tooth tissue engineering.
Luciana Aparecida de Sousa Iwamoto et al. from UNIFESP- Universidade Federal de Sao Paulo- Escola Paulista de Medicina (Brazil) evaluated 4 different methods in 50 premolar teeth, evaluating them via SEM and x-ray, and for weight and colour. The results imply PBS, EDTA, hydrogen peroxide and Ryozime® enzymatic detergent to be the best method available, but it is by no means perfect.
You can read the full, open access piece here.
Reference:
Tooth tissue engineering: tooth decellularization for natural scaffold
Luciana Aparecida de Sousa Iwamoto, Monica Talarico Duailibi, Gerson Yoshinobu Iwamoto, Yara Juliano, Michel Silvio Duailibi, Francisco André Ossamu Tanaka, Silvio Eduardo Duailibi
Future Science OA, FSO121, doi:10.4155/fsoa-2016-0016 (2016).
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