Case Studies: Scaling Cell Therapy Manufacturing

This webinar is no longer available. Gain insights into T-cell expansion, viral vector production and scaling production of mesenchymal stem cells (MSCs) through the use of a functionally closed, automated, cell culture process.


This webinar is no longer available.

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Gain
insights into T-cell expansion, viral vector production and scaling
production of mesenchymal stem cells (MSCs) through the use of a
functionally closed, automated, cell culture process.

Dr. Beltzer
(Terumo BCT, CO, U.S.) will present a number of case studies to
describe how process development and economic goals were achieved in
both industry and academic settings.

Results include up to a 500-fold expansion of T-cells in 12 days,
40 percent reduction in cost of goods for an allogeneic cell therapy,
and automated viral vector production with titers similar to flask-based
processes.

Particular attention will be directed toward the process changes often needed to meet these goals.

What will you learn?

  • New results of T-cell expansion using a hollow-fiber bioreactor system
  • Techniques for scaling production of mesenchymal stem cells (MSCs)
  • New approach to viral vector production
  • Case studies on cost and labor savings achieved

Who may this interest?

  • Clinicians, researchers, lab technologists and cell therapy industry professionals
  • Cell therapy manufacturing professionals
  • Gene and immunotherapy manufacturing professionals

Speaker

Jim Beltzer, PhD
Senior Cell Processing Specialist
Terumo BCT

Prior to joining the Cell Processing team at Terumo BCT, Dr
Beltzer was the lead scientist for the research and development of
Corning® Synthemax®, a synthetic growth surface for the culture of human
embryonic stem cells at Corning Life Sciences. He was a co-founder of
RETT Corporation and was a key player in the industrialization of
several technology platforms, including phage display and yeast
two-hybrid. He has more than 20 years of industrial research and
development experience in a broad range of disciplines.

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