Osteogenic, adipogenic and chondrogenic differentiation of MSCs

In this infographic, Alice Philipson (University of Leeds, UK) provides an overview of different pathways of differentiation for MSCs.

Go to the profile of RegMedNet
May 04, 2018
Upvote 0 Comment

Mesenchymal stem cells (MSCs) have the ability to differentiate into multiple different cell types. In this infographic, Alice Philipson discusses osteogenic, adipogenic and chondrogenic cell culture including the different ways to detect each cell type. Find out more about Alice's research in this episode of TalkingRegMed.

Find out more about MSCs in our latest spotlight

Go to the profile of RegMedNet


eCommunity, Future Science Group

RegMedNet is a networking site where users can share their knowledge and insights. This profile will share some content and updates from the RegMedNet team, including webinars, news and journal articles.


Go to the profile of James L. Sherley, M.D., Ph.D.

A more accurate depiction of these populations would show a small fraction of asymmetrically self-renewing stem cells that divide to produce committed progenitors that accumulate to much higher fraction than the stem cells.  Thereafter, the relationships between the pathways to different differentiation lineages is rather ill-defined.  However, it may be that most committed progenitors can be directed along any of the three described differentiation paths depending on the environmental factors supplemented.  The important correction in knowledge is that described MSC populations, no matter their tissue of origin, are never homogeneous stem cell populations as they are so often erroneously depicted and treated.