Allogeneic cell therapy bioprocess economics and optimization: downstream processing decisions

Written by Regenerative Medicine
Journal articles Manufacturing & scale-up Spotlight on commercialization and translation

In this Regenerative Medicine research article, discover how dose, demand and lot size affects the cost-effectiveness of cell therapy processing. Allogeneic stem cells are showing clinical promise in several therapeutic indications, with regional approvals for graft-versus-host disease and osteoarthritis. In this research article,learn more about a decisional tool to investigate the impact of commercial doses, demands and lot sizes on the cost—effectiveness of scalable, single-use downstream processing and fill finish technologies for cell therapies. Hassan S, Simaria AS, Varadaraju H, Gupta S, Warren K, Farid SS. Allogeneic cell therapy bioprocess economics and optimization: downstream processing decisions. Regen. Med. 10(5), 591—609 (2015)

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