Spotlights
Spotlight on tissue engineering
Tissue engineering in regenerative medicine is a dynamic, multidisciplinary field that involves the application of principles from engineering, biology and materials science. ...
Read moreScaling up for cell and gene therapies
Cell and gene therapies typically require a substantial number of cells per dose and as the number of diseases that can be targeted by contemporary cell and gene therapies expands from ...
Read moreSpotlight on cryopreservation
Cryopreservation plays an integral role in the development, manufacturing and transportation of cell therapies to streamline therapeutics to commercial and clinical development. ...
Read moreAccelerating the CGT landscape at ISCT 2022: interviews on the inside
After two long years, the annual meeting of the International Society for Cell and Gene Therapy (ISCT) was back in person (4-7 May, San Francisco, CA, USA). To make the most of ...
Read moreSpotlight on CAR-T release testing and quality control
The growth of cell therapy around the world means accurate and reliable methods of quantifying dose and circulating cell volume are crucial for ensuring safety and effectiveness. ...
Read moreSpotlight on acellular regenerative medicine
The use of exosomes as a cell-free therapeutic tool requires the production of clinically relevant amounts of high-quality vesicles. However, as every multistep process, the exosome ...
Read moreSpotlight on cell monitoring and imaging
Ineffective cell monitoring and imaging can have a tremendous impact on cell-based therapies in preclinical, translational and clinical research. Novel imaging approaches would enable ...
Read moreSpotlight on iPSC expansion and differentiation
The creation of induced pluripotent stem cells (iPSCs) revolutionized the regenerative medicine field in 2006 when Shinya Yamanaka created his famous pluripotency cocktail of four ...
Read moreSpotlight on bioprinting
In this Spotlight feature, 3DMedNet aims to highlight key bioprinting projects, from conventional biofabrication and regenerative medicine research to novel applications of ‘bedside’ ...
Read moreSpotlight on allogeneic CAR-T
CAR-T therapy involves utilizing a patient’s own T-cells to treat cancer and, as a technique, has rapidly expanded over the past year. However, obtaining patient samples can be ...
Read moreSpotlight on gene therapy
Gene therapy has the potential to eliminate a number of diseases which are currently causing distress to patients and burden on the healthcare system. Gene therapies have been tested in ...
Read moreSpotlight on automation
The manufacture of cell-based products to a clinical standard is a complex and delicate process, but essential in making these therapies more cost-effective and more widely available. ...
Read moreSpotlight on immunotherapy
Immunotherapy is a rapidly developing therapeutic approach that involves harnessing a patient’s immune system to fight disease, often cancer or immune disorders such as allergies. In ...
Read moreSpotlight on MSCs
MSCs can be harvested from several human tissues, or derived from induced pluripotent stem cells (iPSCs), and can differentiate into a range of tissue-specific cells. Various studies ...
Read moreSpotlight on organoids
Organoids offer a unique opportunity to model drugs and diseases in vitro, comprising of a range of organ-specific cell types that are closely biomimetic, enabling more accurate drug ...
Read moreSpotlight on commercialization and translation
This spotlight will provide an insight into the challenges, trends, developments and debates surrounding the many factors that influence the commercial viability of a cell therapy. We ...
Read moreSpotlight on cell therapy regulation
This spotlight on cell therapy regulation will aim to provide insight into challenges, trends, developments and debates in the regulation of cell therapies aimed at regenerative ...
Read moreSpotlight on iPSC production
The first generation of induced pluripotent stem cells (iPSCs) 10 years ago marked a huge milestone in the field, leading to great progress from disease modeling to development of new ...
Read moreSpotlight on MDI Biological Laboratory
The MDI Biological Laboratory is a rapidly growing, independent, nonprofit biomedical research institution. Its mission is to improve human health and well-being through basic research, ...
Read moreSpotlight on wound healing
Many different diseases and injuries such as trauma, surgery, burns, poor circulation and pressure can result in acute or chronic wounds, which can have a significant impact on quality ...
Read moreSpotlight on biomaterials
With the recent boom in 3D printing and the increasing introduction of hydrogels and scaffolds in research and clinical trials, biomaterials are playing a key role in regenerative ...
Read moreSpotlight on KCL’s Centre for Stem Cells & Regenerative Medicine
Spotlight on the aims and expertise of King’s College London’s (KCL’s) Centre for Stem Cells and Regenerative Medicine, which officially opens in December 2015. Located in the Guy’s ...
Read more