Spotlights

Spotlight on CAR-T release testing and quality control

The growth of cell therapy around the world means accurate and reliable methods of quantifying dose and circulating cell volume are crucial for ensuring safety and effectiveness. ...

Spotlight on acellular regenerative medicine

The use of exosomes as a cell-free therapeutic tool requires the production of clinically relevant amounts of high-quality vesicles. However, as every multistep process, the exosome ...

Spotlight on cell monitoring and imaging

Ineffective cell monitoring and imaging can have a tremendous impact on cell-based therapies in preclinical, translational and clinical research. Novel imaging approaches would enable ...

Spotlight on iPSC expansion and differentiation

The creation of induced pluripotent stem cells (iPSCs) revolutionized the regenerative medicine field in 2006 when Shinya Yamanaka created his famous pluripotency cocktail of four ...

Spotlight on allogeneic CAR-T

CAR-T therapy involves utilizing a patient’s own T-cells to treat cancer and, as a technique, has rapidly expanded over the past year. However, obtaining patient samples can be ...

Spotlight on gene therapy

Gene therapy has the potential to eliminate a number of diseases which are currently causing distress to patients and burden on the healthcare system. Gene therapies have been tested in ...

Spotlight on automation

The manufacture of cell-based products to a clinical standard is a complex and delicate process, but essential in making these therapies more cost-effective and more widely available. ...

Spotlight on immunotherapy

Immunotherapy is a rapidly developing therapeutic approach that involves harnessing a patient’s immune system to fight disease, often cancer or immune disorders such as allergies. In ...

Spotlight on MSCs

MSCs can be harvested from several human tissues, or derived from induced pluripotent stem cells (iPSCs), and can differentiate into a range of tissue-specific cells. Various studies ...

Spotlight on organoids

Organoids offer a unique opportunity to model drugs and diseases in vitro, comprising of a range of organ-specific cell types that are closely biomimetic, enabling more accurate drug ...

Spotlight on commercialization and translation

This spotlight will provide an insight into the challenges, trends, developments and debates surrounding the many factors that influence the commercial viability of a cell therapy. We ...

Spotlight on cell therapy regulation

This spotlight on cell therapy regulation will aim to provide insight into challenges, trends, developments and debates in the regulation of cell therapies aimed at regenerative ...

Spotlight on iPSC production

The first generation of induced pluripotent stem cells (iPSCs) 10 years ago marked a huge milestone in the field, leading to great progress from disease modeling to development of new ...

Spotlight on MDI Biological Laboratory

The MDI Biological Laboratory is a rapidly growing, independent, nonprofit biomedical research institution. Its mission is to improve human health and well-being through basic research, ...

Spotlight on wound healing

Many different diseases and injuries such as trauma, surgery, burns, poor circulation and pressure can result in acute or chronic wounds, which can have a significant impact on quality ...

Spotlight on biomaterials

With the recent boom in 3D printing and the increasing introduction of hydrogels and scaffolds in research and clinical trials, biomaterials are playing a key role in regenerative ...

Spotlight on KCL’s Centre for Stem Cells & Regenerative Medicine

Spotlight on the aims and expertise of King’s College London’s (KCL’s) Centre for Stem Cells and Regenerative Medicine, which officially opens in December 2015. Located in the Guy’s ...