Biomaterials for topical and transdermal drug delivery in reconstructive transplantation

Written by Nanomedicine

In this review, published in the journal Nanomedicine, researchers from the Institute for Stem Cell Science & Regenerative Medicine (Karnataka, India) assess the current status of vascularized composite allotransplantation (VCA) and the steps required to progress the filed further in the future. Lifelong systemic immunosuppression remains the biggest challenge in vascularized composite allotransplantation (VCA) due to the adverse effects it causes. Since VCA is a life-enhancing procedure as compared with solid organ transplant which is life-saving; one needs to weigh the benefits and risks carefully. Thus, there is a huge unmet clinical need to design biomaterial-based vehicles that can deliver drugs...

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