Depleting decidual precursor cells linked with pregnancy loss

Scientists from Warwick Medical School at the University of Warwick (Coventry, UK) have discovered that the reduction of decidual precursor cells in the womb lining may lead to recurring pregnancy loss. This research was recently published in the journal STEM CELLS. "This raises the possibility that they can be harnessed to prevent pregnancy disorders," commented corresponding author of the study, Jan J Brosens (Warwick Medical School). During a typical pregnancy, the lining of the womb – known as the endometrium – remodels itself thoroughly. During this process, endometrial stromal cells differentiate into specialized decidual cells that provide plasticity to the...