First patient-derived organoid model developed for cervical cancer

Written by Harriet Wall

A team from the Hubrecht Institute (Utrecht, The Netherlands) has developed the first patient-derived organoid model for cervical cancer. This novel system provides an excellent model to study the human cervix. Their results were recently published in the journal Cell Stem Cell. Organoids, derived from stem cells, are tiny 3D tissue cultures that mimic the function of an organ. In their study, the team developed an organoid-based model for the healthy cervix and associated malignancies including cervical cancer – often caused by a virus known as the human papillomavirus (HPV). "For our study, we used a herpes virus – herpes...

To view this content, please register now for access

It's completely free