In focus: packaging and producer cell lines

Lentiviral vectors are often a popular choice for transient transfection when it comes to developing cell therapies. However, this method can often be expensive, difficult to reproduce at larger scales and can result in contamination of the lentiviral preparation. Packaging and producer cell lines for lentiviral production offers an attractive alternative for this, as they already have elements of the lentiviral packaging system embedded in the cell’s genome.

In our latest In Focus feature, produced in association with OXGENE (Oxford, UK), we bring you expert insights into the advantages that packaging and producer cell lines have, including what applications would be most appropriate for their use. We will also explore how the needs of cell therapy manufacturers have changed over recent years with regards to the use of lentiviral vectors. 

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