Industry updates with Dusko Ilic: August 2025

Written by Dusko ILIC
CAR-T Cell therapy Clinical manufacturing Clinical trials FDA Gene therapy Industry developments iPSCs Manufacturing & scale-up Opinion Regulation & policy Report Stem cells

Every month, Dusko Ilic (King's College London; UK) explores the latest breakthroughs and trends shaping the field in his Industry Updates article for our sister journal Regenerative Medicine. Here, he answers three quick-fire questions about the key insights: what did he expect, what surprised him, and what’s the one story we shouldn’t miss? What happened this month that you were expecting? Immune-evasive islets The New England Journal of Medicine article and Sana Biotechnology’s (WA, USA) press release describes the first-in-human transplantation of gene-edited pancreatic islet cells (UP421) in a patient with long-standing type 1 diabetes, without immunosuppression. Using CRISPR-Cas12b and lentiviral...

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