Analytical solutions to accelerate your AAV gene therapy
Adeno-associated viruses (AAV) are small replication-defective, nonenveloped viruses that are promising vectors in gene therapy. AAVs are the most commonly used viral vectors to deliver healthy genes due to their low immunogenicity, safety and long-term transient expression. Despite this, it can be challenging to ensure efficacy of the final AAV–based gene therapy product. Careful capsid characterization in AAV vectors is key to ensuring final-product purity, quality and safety for patients. View this infographic to learn more about the complexity of AAV gene therapy products and the analytical solutions that can be applied to increase final product efficacy, such as the resDNASEQ system, the ProPac™ SAX-10 HPLC Columns and host cell protein identification and quantification by LC-HRMS.
This content was supplied by Thermo Fisher Scientific.