iPSCs and MSCs: considerations for development and manufacturing

This infographic explores the key challenges in developing and manufacturing induced pluripotent stem cells and mesenchymal stem cells for cell therapy and regenerative medicine. From biological hurdles — such as source variability, genetic stability and cellular senescence, that impact fundamental cellular properties — to process control obstacles like standardization and scalability when transitioning from laboratory research to clinical manufacturing, and finally, regulatory requirements demanding rigorous testing and documentation to satisfy safety and efficacy standards. 

This infographic is part of the RegMedNet In Focus on iPSCs and MSCs, in association with Sartorius. Discover expert opinions on this topic by visiting our feature homepage.

In Focus: iPSCs and MSCs

RMN – 2025 – Q2 – Sartorius – In Focus – MSC iPSCs – infographic – final

Illustrated by Tobias Dumbraveanu (Taylor & Francis Group, London, UK).

This infographic was created in association with Sartorius.