Integration concepts for multi-organ chips: how to maintain flexibility?!

Written by Future Science OA

In this Future Science OA perspective, learn about designing flexible platforms for drug development and disease modelling. Multi-organ platforms have an enormous potential to lead to a paradigm shift in a multitude of research domains including drug development, toxicological screening, personalized medicine as well as disease modeling. Integrating multiple organ—tissues into one microfluidic circulation merges the advantages of cell lines (human genetic background) and animal models (complex physiology) and enables the creation of more in vivo-like in vitro models.  “Together, the technology will help to significantly reduce the use of animal models in the coming years and may lead to...

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