Review of iPSC, direct conversion by trans-differentiation, direct reprogramming and oligodendrocyte differentiation

Written by Regenerative Medicine

Review article by Ankshita Prasad et al. (National University of Singapore) looking at different methods of somatic cell reprogramming cells to generate oligodendrocytes with remyelinating potential, for cell replacement treatment of demyelinating conditions in the CNS. Cellular reprogramming could allow autologous cell therapy for many diseases and injuries. This Review by Ankshita Prasad, Janani Manivannan, Daniel TB Loong, Soo M Chua, Payam M Gharibani & Angelo H All from the National University of Singapore looks at induced pluripotent stem cells, direct conversion and direct reprogramming for generation oligodendrocytes with remyelinating potential that could be used in the clinic for treatment...

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