Stem cells for osteodegenerative diseases: current studies and future outlook

In this Regenerative Medicine review, discover more about stem cell therapies for osteodegenerative disorders. In this Regenerative Medicine review, discover more about stem cell therapies for osteodegenerative disorders Figure 1.‚ Schematic of induced pluripotent stem cell induction. Fibroblasts are harvested from the skin and reprogrammed by inducing expression of Oct-3/4, c-myc, Klf-4 and Sox-2 within the cells, typically by viral integration. Pluripotency of resulting cells is verified by standard assays, including their ability to make chimeric mice, form teratomas and differentiate in vitro into cells of all three germ layers. McClelland Descalzo DL, Ehnes DD, zur Nieden NI. Stem cells...