Regenerative approaches to diabetes and its associated disorders – PDF update
Download, save and read popular articles on diabetes, highlighting key research and thought leadership, with two original Research Articles and a Review.
This month you can download popular articles on diabetes, highlighting key research and thought leadership, with two original Research Articles and a Review.
Delivery of mesenchymal stem cells in biomimetic engineered scaffolds promotes healing of diabetic ulcers
Research Article by Roland Assi, Trenton R Foster, Hao He et al.
In the first article of the PDF supplement, using mesenchymal stem cells contained within a biomimetic rolled collagen scaffold are investigated as a tissue engineering approach to diabetic ulcer wound care in a study by Alan Dardik et al. from Yale University, UCL and Central South University, resulting in improved wound healing in a mouse model.
Selected renal cells modulate disease progression in rodent models of chronic kidney disease via NF-κB and TGF-β1 pathways
Research Article by Andrew T Bruce, Roger M Ilagan, Kelly I Guthrie et al.
The next article in the supplement identifies the mechanistic pathways of selected renal cells delivered as therapy for rodent models of chronic kidney disease – a disease most commonly caused by diabetes. Andrew T Bruce et al. from United Therapeutics conclude that the approach effectively promoted resolution of chronic kidney disease-related etiologies through modulation of the NF-κB signaling pathway.
The role of pharmacogenetics and advances in gene therapy in the treatment of diabetic retinopathy
Review by Aniruddha Agarwal, Sally A Ingham, Keegan A Harkins et al.
The final article in the supplement, a Review by Dong Nguyen et al. from University of Nebraska Medical Center, discusses the role of pharmacogenetics and advances in gene therapy in the treatment of diabetic retinopathy, including anti-tVEGF agents.