Adipose-derived stem cells could help patients with non-healing diabetic foot ulcers

Written by Alice Bough

A team from Wake Forest Institute of Regenerative Medicine (NC, USA) has collaborated with researchers from Universidad Nacional de Nicaragua (Matagalpa, Nicaragua) to test the use of adipose tissue-derived stromal vascular fraction (SVF) cells for the treatment of non-healing diabetic foot ulcers. The results of the Phase I study, published in Stem Cells Translational Medicine, demonstrated that the SVF cells could induce blood vessel formation and accelerate wound healing. “It’s difficult to treat vascular disease and chronic ulcers due to peripheral vascular disease and/or diabetes in resource-poor countries such as Nicaragua,” explained first author of the study, Michael Carstens (Wake...

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