Alginate bioink suitable to bioprint iPSCs to support cartilage repair

Written by Freya Leask

Researchers at Chalmers University of Technology have found that iPSCs could be printed to mimic cartilage utilizing an alginate-based bioink. In a study published in Scientific Report, a team of scientists from Chalmers University of Technology and University of Gothenburg (both Sweden) have demonstrated that a nanofibrillated cellulose (NFC)-alginate composite bioink was suitable to print induced pluripotent stem cells (iPSCs) that formed cartilaginous tissue after 5 weeks. This technology has the potential to form a treatment for cartilage lesions, which can progress into secondary osteoarthritis and cause severe clinical problems. The iPSCs were coprinted with irradiated human chondrocytes and maintained...

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