Brain organoids developed with complex neural activity

Written by Heather Jones

Credit: UCLA Broad Stem Cell Research Center/Nature Neuroscience

Researchers at the University of California Los Angeles (UCLA; CA, USA) have developed brain organoids that exhibit neurological patterns similar to those found in living human brains. The study, published in Nature Neuroscience, broadens the list of brain conditions that can be studied using organoids, with patterns of electrical activity resembling seizures being observed in organoids grown from stem cells derived from individuals with Rett syndrome. This further demonstrates the value of these models in investigating the underlying causes of neurological diseases and testing potential therapies. The past few years has seen progress in researchers’ ability to study the progression...

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