Cells responsible for liver regeneration identified
Credit: UT Southwestern Medical Center (TX, USA)
Researchers from the Children’s Medical Center Research Institute at UT Southwestern (CRI; TX, USA) have identified the group of cells responsible for liver maintenance and regeneration and their location in the liver. This study, published in Science, answers some fundamental questions about liver maintenance, liver damage and liver cancer. While the regenerative power of the liver has been known for centuries, there has been recent debate about whether only a subset of hepatocytes or stem cells across the lobule is responsible for the production of new cells. Previous work in this area was hindered by a lack of markers to...
