Expansion of specific lymphocyte populations with 4Cell® Nutri-T xeno-free, serum-free medium
Developing a successful autologous CAR-T therapy requires the robust expansion of specific subpopulations of immune cells that are derived from the patient. Successful expansion relies on the use of media designed for this specific purpose, preferably those that are chemically defined, xeno-free and serum-free. This is because serum introduces variability into the process, which can lead to a lack of reproducibility and increases risk to the patient.
In this application note, discover the benefits of a xeno- and serum-free medium for selective expansion of cell subpopulations. This includes information about 4Cell® Nutri-T – a medium that has been developed using patient cells and has been optimized for the cultivation of CAR-T cells, tumor infiltrating T lymphocytes and peripheral blood mononuclear cells. Additionally, delve further into how 4Cell® Nutri-T has demonstrated robust performance in comparison to serum-containing and other serum-free medium formulations.
This content was supplied by Sartorius.
