In Focus: CAR-T cell therapy
Despite the great clinical success of CAR-T therapies, due to their complexity manufacturers continue to face a number of challenges, including contamination, variability and cost. In this In Focus, we take a look at the CAR-T therapy development process and the obstacles faced at each step. In our video, infographic and interview we investigate the strategies that could help overcome these barriers to ensure optimum therapeutic quality, safety and efficacy of CAR-T cell therapies.
Infographic
CAR-T Therapy: Overcoming Challenges from Culturing to Commercialization
From harvesting to transduction and onwards to scale–up and manufacture, this infographic investigates how to overcome challenges at every step of the CAR-T therapy process. Discover how to minimize safety concerns and contamination risks, reduce costs and improve cell culture efficiency.
Interview
The revolution of CAR-T technology: an interview with Jalil Hakimi
In this interview with Jalil Hakimi, we discussed the main challenges associated with the development and manufacture of CAR-T therapies and how we can work to overcome them. Jalil also gave his insight into how utilizing CAR-T-specific media is a key factor for generating CAR-T therapies with optimized efficacy and minimized toxicity, which could support a broader range of applications.
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