In Focus: Scalability
Cell expansion allows researchers and cell therapy developers to generate the necessary quantity of cells for their applications. However, cell expansion comes with several challenges, particularly when transitioning from small-scale research to clinical- or commercial-scale manufacturing.
This In Focus feature explores these challenges, including loss of differentiation, heterogeneity, genomic instability, senescence and risks such as contamination, all of which can impact the quality, safety and success of the expanded cells. It also explores how tailored cell expansion services leverage specialized expertise to mitigate these issues, saving time and resources, as well as reducing costs.
Infographic
Meeting the demand for cells: overcoming challenges in scaling up cell culture
Scaling up cell expansion comes with a number of challenges, especially when working with different cell types. This infographic investigates those challenges and explores how researchers and developers can overcome them by utilizing a cost-effective, standardized and quality-controlled cell expansion service.
Interview
Scalability and the role of expertise: an interview with Lisa-Mareike Scheid and Kübra Özer
Lisa-Mareike Scheid and Kübra Özer answer our biggest questions about cell expansion and scalability, from the basics of why cell expansion is so important in regenerative medicine to the complexities of successfully transitioning from small-scale to large-scale cell expansion. We also get an insight into the impact of using a cell expansion service and learn more about the expertise and qualifications of PromoCell’s experts, especially when it comes to dealing with various cell types.
Resources
Mesenchymal stem cells: a cell culture handbook
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