In Focus: Allogeneic cell therapy
Cell therapy is revolutionizing treatment options for rare conditions with unmet medical needs, offering hope to patients who previously had limited options. As the field evolves, the demand for scalable and decentralized solutions grows, necessitated by the need to make advanced treatments accessible to more patients. Allogeneic cell therapy, which uses donor cells to produce therapeutic products, offers a promising alternative to autologous approaches. By enabling the production of treatments for multiple patients, allogeneic therapies have the potential to enhance efficiency, reduce costs and streamline delivery, making transformative treatments more widely available.
In this In Focus feature, PromoCell (Heidelberg, Germany) has partnered with us to share their expertise on allogeneic cell therapies, exploring the challenges and considerations involved in this donor cell-derived method.
Infographic
Challenges and considerations in allogeneic cell therapy manufacturing
This infographic explores the different types of cells used in allogeneic cell therapies, highlighting their applications and addressing the challenges involved in ensuring safety, consistency and scalability. It also examines the advantages and disadvantages of cell freezing, a critical process for preserving cell viability and functionality while supporting reproducible manufacturing at scale.
Interview
Establishing GMP-compliant manufacturing frameworks for scalable allogeneic cell therapies
In this interview, experts Lisa Hamelmann, Lucía Cespón and Iris Bischoff-Kont from PromoCell share their valuable insights on how allogeneic cell therapies are driving the field forward, showing promise in clinical applications. They explore crucial considerations for maintaining cell quality, scaling up production and adhering to regulatory and Good Manufacturing Practice (GMP) requirements – key factors helping allogeneic therapies transition from bench to clinic for patients.
Resources
Cell cryopreservation in Cryo-SFM Plus
In association with PromoCell.
