Spotlight on iPSCs

As the demand for scalable, efficient and safe cell therapies grows, induced pluripotent stem cells (iPSCs) have emerged as a cornerstone technology, offering the potential for both autologous and allogeneic applications. From treating genetic disorders to repairing damaged tissues, their versatility is paving the way for breakthroughs across a range of conditions, including degenerative diseases, immune disorders and cancer. 

In this Spotlight feature, we will examine how iPSCs are being used to develop innovative cell and gene therapies and regenerative medicines and how they can address key challenges in these fields. We will also explore optimized CRISPR-based gene editing for immune oncology applications, streamlined differentiation protocols for producing RPE cells for treating age-related macular degeneration and innovative methodologies for generating iPSC-derived MSCs with exceptional proliferation capacity.