Scaffold-free cell patches possible with simple protocol for engineered adipose-derived stem cells

Cell sheets have previously shown greater efficacy for tissue repair than injections of single stem cells. New research conducted by scientists at the Los Angeles Biomedical Research Institute and Emmaus Life Sciences, Inc. (both CA, USA) has demonstrated the possibility of producing scaffold-free engineered cell sheets. These cell 'patches’ could enable better organ repair follow injury or disease. Injection of stem cells to effect reversal of disease has been proven in the field of bone marrow transplantation for the immune system. However, in the case of organ repair, where stem cells are injected directly into the organ, their uncontrollable migration...