Influence of porosity and pore shape on structural, mechanical and biological properties of poly ϵ-caprolactone electro-spun fibrous scaffolds

Research Article investigating the effects of porosity and pore shape on the properties of electrospun scaffolds, by Kieran P Fuller, Diana Gaspar, Luis M Delgado, Abhay Pandit, Dimitrios I Zeugolis (NUI Galway, Galway, Ireland). Tissue engineered, regenerative therapies will likely require appropriate structural support as well as biomimicry for cell modulation. There are many different approaches for scaffold fabrication, including top-down (e.g., lithography, laser etching, imprinting), bottom-up (e.g., self-assembly, direct writing, melt-spinning, 3D printing, electro-spinning), and nano- and micro-fabrication techniques, but to date a detailed study on the influence of pore shape and porosity on structural, physical and biological properties...