Panel discussion: Strategies for scaling up cell and gene therapies
Cell and gene therapies are one of the fastest growing fields in innovative healthcare, but the high cell yield required for clinical dosage makes the transition from small-scale production to clinical- or commercial-scale manufacturing a challenge. As part of RegMedNet’s Spotlight on scaling up cell and gene therapies, we surveyed the regenerative medicine community to learn more about this topic.
Join our panel of experts as they discuss the insights we uncovered in the survey, key trends in scale-up, benefits and challenges of scaling in bioreactors and their predictions for how emerging technology could improve current scale-up practices.
This webinar was recorded on 4 May 2023.
What will you learn?
- Key scale-up techniques and technologies being utilized by professionals in the field of regenerative medicine
- The greatest challenges faced when navigating scale up
- Areas with potential for growth and optimization
- Future perspectives for advancing scale-up technology
Who may this interest?
- Researchers, developers and manufacturers of cell and gene therapies
- Individuals with an interest in 3D scale-up methodologies
Speakers
Breanna Borys
Bioprocess Scientist
PBS Biotech (CA, USA)
Dr. Breanna Borys is a bioprocess scientist at PBS Biotech (CA, USA). Breanna attended the University of Calgary (Calgary, Canada), where she received her bachelor’s degree in chemical engineering and her PhD in biomedical engineering. In her academic career, Breanna has received numerous prestigious awards, including Engineers Canada Gold Medal Student Award, NSERC Canada Graduate Scholarship and Vanier Canada Graduate Scholarship.
Breanna’s work at PBS Biotech focuses on designing robust and effective scale-up protocols for the expansion of high quality iPSCs to overcome bioprocess bottlenecks and assist customers in bringing life changing cell and gene therapies to market.
Carlos Rodrigues
Researcher
Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa (Lisbon, Portugal)
CellAgri Portugal (Lisbon, Portugal)
Carlos Rodrigues is co-founder and Executive Director of CellAgri Portugal, the Portuguese association for the development of cell agriculture. His research has focused on the scalable cultivation of stem cells in different bioreactor systems using microcarriers or cell aggregates. Carlos holds an MSc in Biological Engineering and a PhD in Bioengineering from Instituto Superior Técnico, University of Lisboa (Lisbon, Portugal). Currently, Carlos is also a researcher at the Institute for Bioengineering and Biosciences at the University of Lisboa and invited assistant professor at Instituto Superior Técnico.
Peter Walters
Fellow of advanced therapies
CRB Group (MO, USA
Peter Walters is a Fellow of Advanced Therapies at CRB with 20 years of experience specializing in biopharmaceutical process and facility design. He has a deep technical background designing equipment and processes for multi-process facilities predicated on maximum flexibility, logistics optimization and technologies that reduce costs while allowing for pipeline expandability and higher quality therapeutics. In addition to leading projects, Peter is responsible for CRB’s companywide strategy and growth in the cell and gene therapy market.
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