ZFDesign: the new gene-ius AI gene-editing tool
Recently developed artificial intelligence program ZFDesign overcomes traditional challenges associated with zinc-finger editing, giving it the potential to overtake alternative gene-editing techniques such as CRISPR.
In a recent study, a team of researchers at the University of Toronto (Canada) and NYU Grossman School of Medicine (NY, USA) designed a novel artificial intelligence program that may, for the first time, allow the hassle-free assembly of target-specific zinc finger (ZF) proteins. Using artificial intelligence to analyze ZF interaction data, the researchers were able to generate a model (ZFDesign) that designs and mimics these interactions to create compatible ZFs. This revolution has particularly promising applications in the gene therapy field.
