How does bone marrow regenerate following chemotherapy?

Written by Harriet Wall

Researchers from Osaka University (Japan) have discovered the molecular mechanism by which hematopoietic stem and progenitor cells (HSPCs) in the bone marrow recover after chemotherapy. This regenerative process was unknown, until now. Their research was recently been published in the Journal of Experimental Medicine. HSPCs give rise to several types of essential blood cells. These cells are particularly vulnerable to treatments such as chemotherapy, due to their rate of division. However, HSPCs have the ability to regenerate after they are damaged. "The bone marrow is a very active organ because it has to constantly produce new blood cells," commented corresponding...

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