Integrated quality control processes for cell therapy workflows using modular benchtop instruments for automation

Automated magnetic bead-based purification systems are transforming CAR T-cell development by streamlining critical workflows and reducing hands-on time by up to 80% while maintaining or exceeding manual method performance across cytokine profiling, sterility testing and nucleic acid isolation. In this Application Note, Thermo Fisher Scientific (MA, USA) demonstrates how a modular benchtop platform enables simultaneous multiplex immunoassay detection of 18 cytokines and sequential DNA/RNA isolation from single samples, addressing key bottlenecks in characterization and quality control processes.

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