Immortalized versus primary cells: considerations for optimal application in cell cultures
Immortalized cell lines are valuable, cost-effective tools for rapid investigation but can have inferior physiological relevance due to the fundamental changes required for immortalization. Primary cell cultures have limited lifespans and are clonally impure but represent a more biologically relevant model. In muscle cell research, the immortalized C2C12 murine line is often used to elucidate fundamental mechanisms but human cells are increasing applied to investigate human muscle differentiation and muscle-related disease. Although primary cell cultures can have a high initial cost, is this outlay worth it for more relevant results? In this whitepaper, discover how to choose the appropriate cell type for your application, considering cell behavior, culture conditions and supply. Plus, learn how Cook MyoSite can support your research through provision of large quantities of high-quality, consistent cells and supportive media. Find out more>>
Watch our webinar on immortalized versus primary cells: considerations for optimal application in cell cultures on demand now. Register and watch now>>
This content was supplied by Cook Myosite.