The importance of HLA for the development of cell therapies
The human leukocyte antigen (HLA) complex is essential for regulating the human defense system. This complex web of cell-surface proteins provides an explanation for individual susceptibility to developing auto-immune diseases, contracting infectious disease and developing cancers. In this White Paper, Lisa Hamelmann (PromoCell; Heidelberg, Germany), provides an understanding of the interplay between HLA and cancer and strategies to harness HLAs in immunotherapies.
This Application Note is part of the RegMedNet In Focus on human leukocyte antigen. Discover expert opinions on this topic by visiting our feature homepage.
This content was supplied by PromoCell.
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Contents:
- HLA restriction: finding and binding
- HLA and diseases: activating autoimmune responses
- HLA and cancer: how cancer cells escape recognition
- New therapeutic options: harnessing HLA for cancer immunotherapy
- HLA-typed cells: an important control system to test new immunotherapies
